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首頁(yè) /藥靶模型 /其他細(xì)胞 /DDR /DLD1-BRCA2-/-

DLD1-BRCA2-/-

CBP75005

產(chǎn)品描述
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I. Introduction
Host Cell: DLD1
Expressed gene: BRCA2
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: RPMI-1640+10%FBS
Storage: Liquid nitrogen
Growth Mode: Adherent
 
II.Background
Breast cancer susceptibility gene (BRCA) is an important tumor suppressor gene, including BRCA1 and BRCA2. The BRCA1/2 gene is an important biomarker for assessing the risk of breast cancer, ovarian cancer and other related cancers, and it is also a biomarker that affects the selection of individualized treatment options for patients.
 
III. Representative Data

1.WB of DLD1-BRCA2-/-

Figure 1. DLD1-BRCA2-KO cell WB data

2. Sanger of DLD1-BRCA2-/-

Figure 2. BRCA2 p.Y42 c.124_125del

3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of DLD-1 BRCA2 KO Cells.

 

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